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 Genomics - Top Downloaded Articles April 2008
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Applications of DNA tiling arrays for whole-genome analysis
Mockler, T.C.; Ecker, J.R.
Volume 85, Issue 1, p. 1 – 15 (January 2005)

285
The current status of cDNA cloning
Harbers, M.
Volume 91, Issue 3, p. 232 – 242 (March 2008)
260
Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis
McCue, M.E.; Valberg, S.J.; Miller, M.B.; Wade, C.; DiMauro, S.; Akman, H.O.; Mickelson, J.R.
Volume 91, Issue 5, p. 458 – 466 (May 2008)
222

Gene expression changes in children with autism
Gregg, J.P.; Lit, L.; Baron, C.A.; Hertz-Picciotto, I.; Walker, W.; Davis, R.A.; Croen, L.A.; Ozonoff, S.; Hansen, R.; Pessah, I.N.; Sharp, F.R.
Volume 91, Issue 1, p. 22 – 29 (January 2008)

215
ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments
Buck, M.J.; Lieb, J.D.
Volume 83, Issue 3, p. 349 - 360 (March 2004)
205
Identification of eight members of the Argonaute family in the human genome*
Sasaki, T.; Shiohama, A.; Minoshima, S.; Shimizu, N.
Volume 82, Issue 3, p. 323 – 330 (September 2003)
187
Integrated approaches to uncovering transcription regulatory networks in mammalian cells
Tan, K.; Tegner, J.; Ravasi, T.
Volume 91, Issue 3, p. 219 – 231 (March 2008)
183
A protein-protein interaction network of transcription factors acting during liver cell proliferation
Gao, J.; Li, W.X.; Feng, S.Q.; Yuan, Y.S.; Wan, D.F.; Han, W.; Yu, Y.
Volume 91, Issue 4, p. 347 – 355 (April 2008)
150
A Comparison of Linkage Disequilibrium Measures for Fine-Scale Mapping
Devlin, B.; Risch, N.
Volume 29, Issue 2, p. 311 – 322 (September 1995)
150
Coexpression, coregulation, and cofunctionality of neighboring genes in eukaryotic genomes
Michalak, P.
Volume 91, Issue 3, p. 243 – 248 (March 2008)
144
A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA
Lee, E.-C.; Yu, D.; Martinez de Velasco, J.; Tessarollo, L.; Swing, D.A.; Court, D.L.; Jenkins, N.A.; Copeland, N.G.
Volume 73, Issue 1, p. 56 – 65 (April 2001)
142
Locked nucleic acids in PCR primers increase sensitivity and performance
Ballantyne, K.N.; van Oorschot, R.A.H.; Mitchell, R.J.
Volume 91, Issue 3, p. 301 – 305 (March 2003)
131
Genome-wide analysis of gene expression profiles during the kernel development of maize (Zea mays L.)
Liu, X.; Fu, J.; Gu, D.; Liu, W.; Liu, T.; Peng, Y.; Wang, J.; Wang, G.
Volume 91, Issue 4, p. 378 – 387 (April 2008)
129
A BAC-based physical map of the apple genome
Han, Y.; Gasic, K.; Marron, B.; Beever, J.E.; Korban, S.S.
Volume 89, Issue 5, p. 630 – 637 (May 2007)
128
Genomic expression patterns distinguish long-term from short-term glioblastoma survivors: A preliminary feasibility study
Marko, N.F.; Toms, S.A.; Barnett, G.H.; Weil, R.
Volume 91, Issue 5, p. 395 – 406 (May 2008)
127

Global, comparative analysis of tissue-specific promoter CpG methylation
Schilling, E.; Rehli, M.
Volume 90, Issue 3, p. 314 – 323 (September 2007)

124
Natural variation in four human collagen genes across an ethnically diverse population
Chan, T.F.; Poon, A.; Basu, A.; Addleman, N.R.; Chen, J.; Phong, A.; Byers, P.H.; Klein, T.E.; Kwok, P.Y.
Volume 91, Issue 4, p. 307 – 314 (April 2008)
124
Improved detection and annotation of transposable elements in sequenced genomes using multiple reference sequence sets
Buisine, N.; Quesneville, H.; Colot, V.
Volume 91, Issue 5, p. 467 – 475 (May 2008)
124
Genes regulating the serotonin metabolic pathway in the brain stem and their role in the etiopathogenesis of the sudden infant death syndrome
Nonnis Marzano, F.; Maldini, M.; Filonzi, L.; Lavezzi, A.M.; Parmigiani, S.; Magnani, C.; Bevilacqua, G.; Matturri, L.
Volume 91, Issue 6, p. 485 – 491 (June 2008)
122

Gene expression profiling in the adult Down syndrome brain
Lockstone, H.E.; Harris, L.W.; Swatton, J.E.; Wayland, M.T.; Holland, A.J.; Bahn, S.
Volume 90, Issue 6, p. 647 – 660 (December 2007)

119
Transcriptional and epigenetic status of protamine 1 and 2 genes following round spermatids injection into mouse oocytes
Borghol, N.; Blachere, T.; Lefevre, A.
Volume 91, Issue 5, p. 415 – 422 (May 2008)
113
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
Altenberg, B.; Greulich, K.O.
Volume 84, Issue 6, p. 1014 – 1020 (December 2004)
111
Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
Pruunsild, P.; Kazantseva, A.; Aid, T.; Palm, K.; Timmusk, T.
Volume 90, Issue 3, p. 397 – 406 (September 2007)
111
Combinatorial effects of four histone modifications in transcription and differentiation
Fischer, J.J.; Toedling, J.; Krueger, T.; Schueler, M.; Huber, W.; Sperling, S.
Volume 91, Issue 1, p. 41 – 51 (January 2008)
106
Evolution in the laboratory: The genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1
Pfeiffer, F.; Schuster, S.C.; Broicher, A.; Falb, M.; Palm, P.; Rodewald, K.; Ruepp, A.; Soppa, J.; Tittor, J.; Oesterhelt, D.
Volume 91, Issue 4, p. 335 – 346 (April 2008)
103
New isoforms of rat Aquaporin-4
Moe, S.E.; Sorbo, J.G.; Sogaard, R.; Zeuthen, T.; Petter Ottersen, O.; Holen, T.
Volume 91, Issue 4, p. 367 – 377 (April 2008)
102
Transgenerational epigenetic programming of the embryonic testis transcriptome
Anway, M.D.; Rekow, S.S.; Skinner, M.K.
Volume 91, Issue 1, p. 30 – 40 (January 2008)
100
A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction
Adams, D.J.; Quail, M.A.; Cox, T.; van der Weyden, L.; Gorick, B.D.; Su, Q.; Chan, W.i.; Davies, R.; Bonfield, J.K.; Law, F.; Humphray, S.; Plumb, B.; Liu, P.; Rogers, J.; Bradley, A.
Volume 86, Issue 6, p. 753 – 758 (December 2005)
95
Gene expression profiling in livers of mice after acute inhibition of @b-oxidation
van der Leij, F.R.; Bloks, V.W.; Grefhorst, A.; Hoekstra, J.; Gerding, A.; Kooi, K.; Gerbens, F.; te Meerman, G.; Kuipers, F.
Volume 90, Issue 6, p. 680 – 689 (December 2007)
91
Resolving the resolution of array CGH
Coe, B.P.; Ylstra, B.; Carvalho, B.; Meijer, G.A.; MacAulay, C.; Lam, W.L.
Volume 89, Issue 5, p. 647 – 653 (May 2007)
89
Functional classification analysis of somatically mutated genes in human breast and colorectal cancers
Chittenden, T.W.; Howe, E.A.; Culhane, A.C.; Sultana, R.; Taylor, J.M.; Holmes, C.; Quackenbush, J.
Volume 91, Issue 6, p. 508 – 511 (June 2008)
89
Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma
Wu, J.; Qin, Y.; Li, B.; He, W.z.; Sun, Z.l.
Volume 91, Issue 5, p. 443 – 450 (May 2008)
88
Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos
Bergeron, S.A.; Milla, L.A.; Villegas, R.; Shen, M.C.; Burgess, S.M.; Allende, M.L.; Karlstrom, R.O.; Palma, V.
Volume 91, Issue 2, p. 165 – 177 (February 2008)
87
Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection
Mukherjee, S.; Nagajyothi, F.; Mukhopadhyay, A.; Machado, F.S.; Belbin, T.J.; Campos de Carvalho, A.; Guan, F.; Albanese, C.; Jelicks, L.A.; Lisanti, M.P.; Silva, J.S.; Spray, D.C.; Weiss, L.M.; Tanow
Volume 91, Issue 5, p. 423 – 432 (May 2008)
87
Appearance of new tetraspanin genes during vertebrate evolution
Garcia-Espana, A.; Chung, P.J.; Sarkar, I.N.; Stiner, E.; Sun, T.T.; DeSalle, R.
Volume 91, Issue 4, p. 326 – 334 (April 2008)
86
Global functional profiling of gene expression
Draghici, S.; Khatri, P.; Martins, R.P.; Ostermeier, G.C.; Krawetz, S.A.
Volume 81, Issue 2, p. 98 – 104, (February 2003)
85
Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences
Cohen, S.M.; Hatada, S.; Brylawski, B.P.; Smithies, O.; Kaufman, D.G.; Cordeiro-Stone, M.
Volume 84, Issue 3, p. 475 – 484 (September 2004)
84
Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system
Haitina, T.; Lindblom, J.; Renstrom, T.; Fredriksson, R.
Volume 88, Issue 6, p. 779 – 790 (December 2006)
84
A substitution mutation in the myosin binding protein C gene in ragdoll hypertrophic cardiomyopathy
Meurs, K.M.; Norgard, M.M.; Ederer, M.M.; Hendrix, K.P.; Kittleson, M.D.
Volume 90, Issue 2, p. 261 – 264 (August 2007)
84
Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid
Twiner, M.J.; Ryan, J.C.; Morey, J.S.; Smith, K.J.; Hammad, S.M.; Van Dolah, F.M.; Hess, P.; McMahon, T.; Satake, M.; Yasumoto, T.; Doucette, G.J.
Volume 91, Issue 3, p. 289 – 300 (March 2008)
84

Thermal asymmetric interlaced PCR: automatable amplification and sequencing of insert end fragments from P1 and YAC clones for chromosome walking
Liu, Y.-G.; Whittier, R.
Volume 25, Issue 3, p. 674 – 681 (February 1995)

77
Dynamic gene expression during the onset of myoblast differentiation in vitro
Delgado, I.; Huang, X.; Jones, S.; Zhang, L.; Hatcher, R.; Gao, B.; Zhang, P.
Volume 82, Issue 2, p. 109 – 121 (August 2003)
77
DHPC: A new tool to express genome structural features
Deng, X.; Deng, X.; Rayner, S.; Liu, X.; Zhang, Q.; Yang, Y.; Li, N.
Volume 91, Issue 5, p. 476 – 483 (May 2008)
77
Individual histone deacetylases in Drosophila modulate transcription of distinct genes
Cho, Y.; Griswold, A.; Campbell, C.; Min, K.T.
Volume 86, Issue 5, p. 606 – 617 (November 2005)
74
The ascent of cat breeds: Genetic evaluations of breeds and worldwide random-bred populations
Lipinski, M.J.; Froenicke, L.; Baysac, K.C.; Billings, N.C.; Leutenegger, C.M.; Levy, A.M.; Longeri, M.; Niini, T.; Ozpinar, H.; Slater, M.R.; Pedersen, N.C.; Lyons, L.A.
Volume 91, Issue 1, p. 12 – 21 (January 2008)
71
ENCODE and ChIP-chip in the genome era
Boguski, M.S.
Volume 83, Issue 3, p. 347 – 348 (March 2004)
70
Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development
Fernandes, J.M.O.; Macqueen, D.J.; Lee, H.T.; Johnston, I.A.
Volume 91, Issue 4, p. 315 – 325 (April 2008)
70
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels
Cervino, A.C.; Li, G.; Edwards, S.; Zhu, J.; Laurie, C.; Tokiwa, G.; Lum, P.Y.; Wang, S.; Castellini, L.W.; Lusis, A.J.; Carlson, S.; Sachs, A.B.; Schadt, E.E.
Volume 86, Issue 5, p. 505 – 517 (November 2005)
68
Sensory genes and mate choice: Evidence that duplications, mutations, and adaptive evolution alter variation in mating cue genes and their receptors
Horth, L.
Volume 90, Issue 2, p. 159 – 175 (August 2007)
67
A Modular, Positive Selection Bacterial Artificial Chromosome Vector with Multiple Cloning Sites
Frengen, E.; Weichenhan, D.; Zhao, B.; Osoegawa, K.; van Geel, M.; de Jong, P.J.
Volume 58, Issue 3, p. 250 – 253 (June 1999)
67
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